====== List of Autoantibodies ======

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===== Autoantibodies =====

<sortable>
^ Abbreviation ^ Autoantibodies ^
| Anti-dsDNA | Anti-double stranded DNA |
| Anti-nRNP (anti-U1-RNP) | Anti-nuclear ribonucleoprotein |
| Anti-Scl-70 | Anti-topoisomerase I |
| Anti-Sm | Anti-Smith |
| Anti-SSA (Anti-Ro) | Anti-(Sjögren's syndrome type A angigen) |
| Anti-SSB (Anti-La) | Anti-(Sjögren's syndrome type B angigen) |
| C-ANCA | Cytoplasmic antineutrophil cytoplasmic antibodies |
| MPO-ANCA | myeloperoxidase ANCA |
| PR3-ANCA | proteinase 3 ANCA |
| P-ANCA | Perinuclear anti-neutrophil cytoplasmic antibodies |
</sortable>

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===== Autoimmune Diseases =====

<sortable>
^ Abbreviation ^ Autoimmune Diseases ^
| DM | [[Dermatomyositis]] |
| MCTD | [[Mixed connective tissue disease]] |
| PAN | [[Polyarteritis nodosa]] |
| PM | [[Polymyositis]] |
| SjS | [[Sjögren's syndrome]] |
| SLE | [[Systemic lupus erythematosus]] |
| SSc | [[Systemic sclerosis]] |
</sortable>

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===== Autoantibodies and Diseases =====

<sortable>
^ Autoantibodies ^ Diseases ^
| Anti-centromere | Limited cutaneous SSc |
| Anti-dsDNA | SLE |
| Anti-histone | Drug induced SLE |
| Anti-Jo-1 | PM/DM (specific, not sensitive) |
| Anti-La | SLE (can be positive)\\ SjS (sensitive, not specific) |
| Anti-Mi-2 | PM/DM (specific, not sensitive) |
| Anti-Scl-70 | CREST syndrome (centromere pattern)\\ Diffuse cutaneous SSc (nucleus pattern; specific, not sensitive)\\ SLE (can be positive) |
| Anti-Sm | SLE (specific, not sensitive) |
| Anti-SRP | DM/PM |
| Anti-RNA synthetase | Anti-synthetase syndrome |
| Anti-Ro | SLE (can be positive)\\ SjS (sensitive, not specific) |
| Anti-U1 RNP | MCTD (sensitive, not specific)\\ SLE (can be positive) |
| c-ANCA | Granulomatous polyangiitis |
| p-ANCA | Microscopic polyangiitis\\ PAN |
</sortable>

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===== References =====

  * Birtane M. [[https://archivesofrheumatology.org/full-text/453|Diagnostic Role of Anti-Nuclear Antibodies in Rheumatic Diseases]]. Turk J Rheumatol 2012;27(2):79-89. DOI: 10.5606/tjr.2012.013
  * Jury EC, D'Cruz D, Morrow WJW. [[https://jcp.bmj.com/content/54/5/340|Autoantibodies and overlap syndromes in autoimmune rheumatic disease]]. Journal of Clinical Pathology 2001;54:340-347.
  * Lee AY, Ang EB. [[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141620/|A clinical overview of autoantibodies in general practice rheumatology]]. Br J Gen Pract. 2014;64(626):e599–e601. DOI:10.3399/bjgp14X681601
  * Oxford Medical Education. [[http://www.oxfordmedicaleducation.com/rheumatology/antibodies-in-rheumatology/|Antibodies in rheumatology]]. Retrieved on 2020-02-15.
  * Schur PH. [[https://www.the-rheumatologist.org/article/know-your-labs/|Know Your Labs]]. Last updated 2009-02-01 and retrieved on 2020-02-15.
  * Tong L, Koh V, Thong BY. [[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557906/|Review of autoantigens in Sjögren's syndrome: an update]]. J Inflamm Res. 2017;10:97–105. DOI:10.2147/JIR.S137024